Randomized, double-blind trial comparing indinavir alone, zidovudine alone and indinavir plus zidovudine in antiretroviral therapy-naive hiv-infected individuals with CD4 cell counts between 50 and 250/mm3

Treatment with indinavir has been shown to result in marked decreases in viral load and increases in CD4 cell counts in HIV-infected individuals. A randomized double-blind study to evaluate the efficacy of indinavir alone (800 mg q8h), zidovidine alone (200 mg q8h) or the combination was performed t...

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Autors principals:	David S. LEWI, Jamal M. SULEIMAN, David E. UIP, Rogerio J. PEDRO, Rosa A. SOUZA, Grace S. SULEIMAN, Conceição ACCETTURI, Olavo M. LEITE, William B. ABREU, Artur O. KALICHMAN, Joaquim P.P. MORAES-FILHO, Eduardo F. MOTTI, Maria Lucia C. PECORARO, Mark R. MAKURATH, Michael L. NESSLY, Randi Y. LEAVITT
Format:	Artigo
Idioma:	Inglês
Publicat:	Universidade de São Paulo (USP) 2000-02-01
Col·lecció:	Revista do Instituto de Medicina Tropical de São Paulo
Matèries:	Randomized study Double blind clinical trial HIV AIDS Protease inhibitors Indinavir Zidovudine Disease progression Therapy Clinical endpoint
Accés en línia:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652000000100005&tlng=en
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