A label free chemoproteomic-based platform to disclose cannabidiol molecular mechanism of action on chronic myelogenous leukemia cancer cells

The discovery of the interactome of cannabidiol (CBD), a non-psychoactive cannabinoid from Cannabis sativa L., has been here performed on chronic myelogenous leukemia cancer cells, using an optimized chemo-proteomic stage, which links Drug Affinity Responsive Target Stability with Limited Proteolysi...

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Detalhes bibliográficos

Principais autores:	Sara Ceccacci, Lorenzo Corsi, Lucio Spinelli, Clarissa Caroli, Matilde Marani, Lisa Anceschi, Matteo Mozzicafreddo, Federica Pellati, Maria Chiara Monti
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-01-01
coleção:	Heliyon
Assuntos:	Cannabidiol Chronic myelogenous leukemia Drug Affinity Responsive Target Stability Limited proteolysis Chemo-proteomics Mass spectrometry
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844024002275
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