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Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment

Abstract Background Pancreatic cancer is one of the most lethal type of cancers, with an overall five-year survival rate of less than 5%. It is usually diagnosed at an advanced stage with limited therapeutic options. To date, no effective treatment options have demonstrated long-term benefits in adv...

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Wedi'i Gadw mewn:
Prif Awduron: Chin-King Looi, Felicia Fei-Lei Chung, Chee-Onn Leong, Shew-Fung Wong, Rozita Rosli, Chun-Wai Mai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2019-04-01
Cyfres:Journal of Experimental & Clinical Cancer Research
Pynciau:
Pancreatic cancer
Immunotherapy
Tumor microenvironment
Mynediad Ar-lein:http://link.springer.com/article/10.1186/s13046-019-1153-8
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