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Tumor-associated macrophages (TAMs): Constructing an immunosuppressive microenvironment bridge for pancreatic ductal adenocarcinoma (PDAC)

Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with increasing incidences worldwide. The overall 5-year survival rate remains low, underscoring the urgent need for effective therapies. Despite the promising efficacy of immunotherapy for various solid tumors, its benefits for pancreatic c...

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Principais autores: Runjie Liu, Jianang Li, Liang Liu, Wenquan Wang, Jinbin Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-05-01
coleção:Cancer Pathogenesis and Therapy
Assuntos:
Pancreatic cancer
Macrophages
Tumor microenvironment
Immunosuppression
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2949713224000557
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