Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

Phosphatidylinositol 3-phosphate (PI(3)P) levels in Plasmodium falciparum correlate with tolerance to cellular stresses caused by artemisinin and environmental factors. However, PI(3)P function during the Plasmodium stress response was unknown. Here, we used PI3K inhibitors and antimalarial agents t...

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Prif Awduron:	Kuan-Yi Lu, Charisse Flerida A Pasaje, Tamanna Srivastava, David R Loiselle, Jacquin C Niles, Emily Derbyshire
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	eLife Sciences Publications Ltd 2020-09-01
Cyfres:	eLife
Pynciau:	phosphatidylinositol 3-phosphate Hsp70 heat stress malaria digestive vacuole
Mynediad Ar-lein:	https://elifesciences.org/articles/56773
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