Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

Phosphatidylinositol 3-phosphate (PI(3)P) levels in Plasmodium falciparum correlate with tolerance to cellular stresses caused by artemisinin and environmental factors. However, PI(3)P function during the Plasmodium stress response was unknown. Here, we used PI3K inhibitors and antimalarial agents t...

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Autors principals:	Kuan-Yi Lu, Charisse Flerida A Pasaje, Tamanna Srivastava, David R Loiselle, Jacquin C Niles, Emily Derbyshire
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2020-09-01
Col·lecció:	eLife
Matèries:	phosphatidylinositol 3-phosphate Hsp70 heat stress malaria digestive vacuole
Accés en línia:	https://elifesciences.org/articles/56773
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