scRNA-Seq reveals age-dependent microglial evolution as a determinant of immune response following spinal cord injury

Spinal cord injury (SCI) is a debilitating condition of the central nervous system (CNS) that leads to severe impairments in sensory and motor functions. Previous studies have pointed out that patient age is a critical factor influencing SCI prognosis. However, the role of microglia in age-related d...

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Principais autores:	Lufei Shao, Yueliang Chang, Jinfang Liu, Leilei Lin, Long Chang, Jialin Zhang, Zhibin Lan, Honglai Zhang, Xiaolei Chen
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2024-12-01
叢編:	Brain Research Bulletin
主題:	Microglial evolution Immune response Age-dependent differences Spinal cord injury Single-cell RNA sequencing
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S0361923024002508
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