E‐selectin affinity glycoproteomics reveals neuroendocrine proteins and the secretin receptor as a poor‐prognosis signature in colorectal cancer

Colorectal cancer (CRC) cells express sialylated Lewis antigens (sLe), crucial for metastasis via E‐selectin binding. However, these glycoepitopes lack cancer specificity, and E‐selectin‐targeted glycoproteins remain largely unknown. Here, we established a framework for identifying metastasis‐linked...

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Bibliografische gegevens

Hoofdauteurs:	Sofia Cotton, Dylan Ferreira, Marta Relvas‐Santos, Andreia Brandão, Luís Pedro Afonso, Andreia Miranda, Eduardo Ferreira, Beatriz Santos, Martina Gonçalves, Paula Lopes, Lúcio Lara Santos, André M. N. Silva, José Alexandre Ferreira
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2025-03-01
Reeks:	Molecular Oncology
Onderwerpen:	cancer glycoproteome colorectal cancer E‐selectin metastasis secretin receptor
Online toegang:	https://doi.org/10.1002/1878-0261.13733
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