Fabrication and Appraisal of Simvastatin via Tailored Niosomal Nanovesicles for Transdermal Delivery Enhancement: In Vitro and In Vivo Assessment

Simvastatin (SIM) is a HMG-CoA reductase inhibitor employed in the management of hyperlipidemia. However, its low bioavailability limits its clinical efficacy. The objective of this study was to overcome the poor bioavailability of SIM via the transdermal application of a SIM-loaded niosomal gel. Ni...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Heba F. Salem, Rasha M. Kharshoum, Heba A. Abou-Taleb, Hanan Osman Farouk, Randa Mohammed Zaki
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2021-01-01
Σειρά:	Pharmaceutics
Θέματα:	thin-film hydration method niosomes factorial design skin permeation transdermal delivery
Διαθέσιμο Online:	https://www.mdpi.com/1999-4923/13/2/138
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