Fabrication and Appraisal of Simvastatin via Tailored Niosomal Nanovesicles for Transdermal Delivery Enhancement: In Vitro and In Vivo Assessment

Simvastatin (SIM) is a HMG-CoA reductase inhibitor employed in the management of hyperlipidemia. However, its low bioavailability limits its clinical efficacy. The objective of this study was to overcome the poor bioavailability of SIM via the transdermal application of a SIM-loaded niosomal gel. Ni...

Descrición completa

Detalles Bibliográficos

Principais autores:	Heba F. Salem, Rasha M. Kharshoum, Heba A. Abou-Taleb, Hanan Osman Farouk, Randa Mohammed Zaki
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-01-01
Series:	Pharmaceutics
Assuntos:	thin-film hydration method niosomes factorial design skin permeation transdermal delivery
Acceso en liña:	https://www.mdpi.com/1999-4923/13/2/138
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!