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A Primate-Specific Isoform of PLEKHG6 Regulates Neurogenesis and Neuronal Migration

Summary: The mammalian neocortex has undergone remarkable changes through evolution. A consequence of such rapid evolutionary events could be a trade-off that has rendered the brain susceptible to certain neurodevelopmental and neuropsychiatric conditions. We analyzed the exomes of 65 patients with...

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Autors principals: Adam C. O’Neill, Christina Kyrousi, Johannes Klaus, Richard J. Leventer, Edwin P. Kirk, Andrew Fry, Daniela T. Pilz, Tim Morgan, Zandra A. Jenkins, Micha Drukker, Samuel F. Berkovic, Ingrid E. Scheffer, Renzo Guerrini, David M. Markie, Magdalena Götz, Silvia Cappello, Stephen P. Robertson
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018-12-01
Col·lecció:Cell Reports
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2211124718317753
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