L1210 Cells Overexpressing ABCB1 Drug Transporters Are Resistant to Inhibitors of the N- and O-glycosylation of Proteins

Overexpression of P-glycoprotein (P-gp, drug transporter) in neoplastic cells is the most frequently observed molecular cause of multidrug resistance. Here, we show that the overexpression of P-gp in L1210 cells leads to resistance to tunicamycin and benzyl 2-acetamido-2-deoxy-α-d-galactopyranoside...

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Autors principals:	Lucia Pavlikova, Mario Seres, Milan Hano, Viera Bohacova, Ivana Sevcikova, Tomas Kyca, Albert Breier, Zdena Sulova
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2017-07-01
Col·lecció:	Molecules
Matèries:	L1210 cells P-glycoprotein multidrug resistance N-glycosylation O-glycosylation tunicamycin benzyl 2-acetamido-2-deoxy-α- ">d-galactopyranoside ubiquitination
Accés en línia:	https://www.mdpi.com/1420-3049/22/7/1104
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