CIGB-258, a Potential Novel Approach to Treat Sepsis-like Hyperinflammation, Reduces Gastrointestinal Hemorrhage in Zebrafish Exposed to Carboxymethyllysine and Ethanol

<b>Objective:</b> CIGB-258 is a 3 KDa altered peptide ligand recognized for its anti-inflammatory activity. Herein, the effect of CIGB-258 was assessed against carboxymethyllysine (CML) and ethanol (Et-OH)-induced sepsis-like events in zebrafish (<i>Danio rerio</i>). <b>Methodology:</b> Adult zebraf...

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Detalhes bibliográficos

Principais autores:	Kyung-Hyun Cho, Yunki Lee, Sang Hyuk Lee, Ashutosh Bahuguna, María del Carmen Domínguez-Horta, Gillian Martínez-Donato
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-03-01
coleção:	Pharmaceuticals
Assuntos:	CIGB-258 (Jusvinza<sup>®</sup>) carboxymethyllysine inflammation intestine interleukin-6 oxidative stress
Acesso em linha:	https://www.mdpi.com/1424-8247/19/3/510
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