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Proteomic Profile Regulated by the Immunomodulatory Jusvinza Drug in Neutrophils Isolated from Rheumatoid Arthritis Patients

Jusvinza is an immunomodulatory drug composed of an altered peptide ligand (APL) designed from a novel CD4+ T cell epitope of human heat shock protein 60 (HSP60), an autoantigen involved in the pathogenesis of rheumatoid arthritis (RA). The peptide induces regulatory T cells and decreases levels of...

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Principais autores: Mabel Hernández-Cedeño, Arielis Rodríguez-Ulloa, Yassel Ramos, Luis J. González, Anabel Serrano-Díaz, Katharina Zettl, Jacek R. Wiśniewski, Gillian Martinez-Donato, Gerardo Guillen-Nieto, Vladimir Besada, María del Carmen Domínguez-Horta
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-11-01
Serier:Biomedicines
Fag:
proteomics
CIGB-814
CIGB-258
Jusvinza
inflammation
NETosis
Online adgang:https://www.mdpi.com/2227-9059/12/12/2740
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