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Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts.

Alterations of mitochondrial DNA copy number (mtDNAcn) in the blood (mitochondrial to nuclear DNA ratio) appear associated with several systemic diseases, including primary mitochondrial disorders, carcinogenesis, and hematologic diseases. Measuring mtDNAcn in DNA extracted from whole blood (WB) ins...

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Bibliografski detalji
Glavni autori: Yamilee Hurtado-Roca, Marta Ledesma, Monica Gonzalez-Lazaro, Raquel Moreno-Loshuertos, Patricio Fernandez-Silva, Jose Antonio Enriquez, Martin Laclaustra
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2016-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC5063275?pdf=render
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