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Guidance receptor degradation is required for neuronal connectivity in the Drosophila nervous system.

Axon pathfinding and synapse formation rely on precise spatiotemporal localization of guidance receptors. However, little is known about the neuron-specific intracellular trafficking mechanisms that underlie the sorting and activity of these receptors. Here we show that loss of the neuron-specific v...

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Autori principali: W Ryan Williamson, Taehong Yang, Jonathan R Terman, P Robin Hiesinger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2010-12-01
Serie:PLoS Biology
Accesso online:http://europepmc.org/articles/PMC2998435?pdf=render
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