Structure-Based Virtual Screening and Biological Evaluation of Peptide Inhibitors for Polo-Box Domain
The polo-box domain of polo-like kinase 1 (PLK1-PBD) is proved to have crucial roles in cell proliferation. Designing PLK1-PBD inhibitors is challenging due to their poor cellular penetration. In this study, we applied a virtual screening workflow based on a combination of structure-based pharmacoph...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI AG
2019-12-01
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| Sarja: | Molecules |
| Aiheet: | |
| Linkit: | https://www.mdpi.com/1420-3049/25/1/107 |
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