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The diamidine DB75 targets the nucleus of <it>Plasmodium falciparum</it>

<p>Abstract</p> <p>Background</p> <p>DB289, [2,5-bis(4-amidinophenyl)furan <it>bis-O</it>-methylamidoxime], is a broad spectrum anti-parasitic compound which has been shown to be effective against malaria in recent clinical trials. DB75, [2,5-bis(4-amidinophenyl)furan], is the active metabolite of t...

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Príomhchruthaitheoirí: Meshnick Steven R, Tidwell Richard R, Purfield Anne E
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2009-05-01
Sraith:Malaria Journal
Rochtain ar líne:http://www.malariajournal.com/content/8/1/104
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