Resistance to Antimalarials in Southeast Asia and Genetic Polymorphisms in pfmdr1

Resistance to antimalarial drugs is a public health problem worldwide. Molecular markers for drug-resistant malaria, such as pfcrt and pfmdr1 polymorphisms, could serve as useful surveillance tools. To evaluate this possibility, sequence polymorphisms in pfcrt (position 76) and pfmdr1 (positions 86,...

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Autors principals: Pickard, Amy L., Wongsrichanalai, Chansuda, Purfield, Anne, Kamwendo, Deborah, Emery, Kathryn, Zalewski, Christy, Kawamoto, Fumihiko, Miller, R. Scott, Meshnick, Steven R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC166057/
https://ncbi.nlm.nih.gov/pubmed/12878499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2418-2423.2003
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