Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

Abstract Background Cell-free plasma mitochondrial DNA (mtDNA) levels are associated with endothelial dysfunction and differential outcomes in critical illness. A substantial alteration in metabolic homeostasis is commonly observed in severe critical illness. We hypothesized that metabolic profiles...

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主要な著者:	Pär I. Johansson, Kiichi Nakahira, Angela J. Rogers, Michael J. McGeachie, Rebecca M. Baron, Laura E. Fredenburgh, John Harrington, Augustine M. K. Choi, Kenneth B. Christopher
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2018-12-01
シリーズ:	Critical Care
主題:	Mitochondrial DNA Metabolite Metabolomics Homeostasis Critical illness Acylcarnitine
オンライン･アクセス:	http://link.springer.com/article/10.1186/s13054-018-2275-7
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