A Herpesviral induction of RAE-1 NKG2D ligand expression occurs through release of HDAC mediated repression

Natural Killer (NK) cells are essential for control of viral infection and cancer. NK cells express NKG2D, an activating receptor that directly recognizes NKG2D ligands. These are expressed at low level on healthy cells, but are induced by stresses like infection and transformation. The physiologica...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Trever T Greene, Maria Tokuyama, Giselle M Knudsen, Michele Kunz, James Lin, Alexander L Greninger, Victor R DeFilippis, Joseph L DeRisi, David H Raulet, Laurent Coscoy
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	eLife Sciences Publications Ltd 2016-11-01
Цуврал:	eLife
Нөхцлүүд:	NK cells NKG2D histone deacetylase herpesviruses NKG2D ligands CK2
Онлайн хандалт:	https://elifesciences.org/articles/14749
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!