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NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment

The antitumor functions of NK cells are regulated by the integration of positive and negative signals triggered by numerous membrane receptors present on the NK cells themselves. Among the main activating receptors, NKG2D binds several stress-induced molecules on tumor targets. Engagement of NKG2D b...

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Auteurs principaux: Alexandra Frazao, Louise Rethacker, Meriem Messaoudene, Marie-Françoise Avril, Antoine Toubert, Nicolas Dulphy, Anne Caignard
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019-03-01
Collection:Frontiers in Immunology
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Accès en ligne:https://www.frontiersin.org/article/10.3389/fimmu.2019.00661/full
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