Sirtuins regulate macrophage polarization in heart failure: Metabolic reprogramming, epigenetic regulation, and immune cell interactions

Heart failure (HF) is an end-stage cardiovascular syndrome caused by structural or functional cardiac abnormalities. Its high morbidity and mortality underscore the urgent need for novel therapeutic strategies. In recent years, the dynamic regulatory mechanisms underlying macrophage polarization in...

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Detalles Bibliográficos

Principais autores:	Ruifang Lin, Yun Zhu, Yongjun Liu, Zhihua Guo, Jiaming Wei, Ya Li, Yunfeng Yu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-10-01
Series:	Pharmacological Research
Assuntos:	Sirtuins Macrophage polarization Heart failure Metabolic reprogramming Epigenetic regulation Immune cell interaction
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S1043661825003615
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