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Immune checkpoint pathways in glioblastoma: a diverse and evolving landscape

Immune checkpoint (IC) inhibition in glioblastoma (GBM) has not shown promising results in the last decade compared to other solid tumors. Several factors contributing to the lack of immunotherapy response include the profound immunosuppressive nature of GBM, highly redundant signaling pathways unde...

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Autori principali: Julio F. Inocencio, Stefan Mitrasinovic, Mohammad Asad, Ian F. Parney, Xingxing Zang, Benjamin T. Himes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-09-01
Serie:Frontiers in Immunology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1424396/full
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