Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model

Combination immunotherapy has emerged as a promising strategy to increase the immune response in glioblastoma (GBM) and overcome the complex immunosuppression occurring in its microenvironment. In this study, we hypothesized that combining DNA vaccines—to stimulate a specific immune response—and dua...

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Auteurs principaux:	Mathilde Bausart, Kevin Vanvarenberg, Bernard Ucakar, Alessandra Lopes, Gaëlle Vandermeulen, Alessio Malfanti, Véronique Préat
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2022-05-01
Collection:	Pharmaceutics
Sujets:	glioblastoma plasmid DNA vaccine immune checkpoint blockade combination immunotherapy
Accès en ligne:	https://www.mdpi.com/1999-4923/14/5/1025
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