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Peptide Coacervates Promote Cytosolic Delivery of STING Agonists for Cancer Immunotherapy

<b>Background</b><b>/Objectives:</b> Cyclic dinucleotide stimulator of interferon genes (STING) agonists have emerged as potential agents in cancer immunotherapy, but their clinical applications are limited by relatively poor pharmacokinetic properties. <b>Methods</b>: A luciferase reporter assay wa...

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Main Authors: Wenlv Zheng, Wei Tang, Jianzheng Wang, Yurong Li, Shengnan Wang, Dan Wu, Xiaoquan Wang, Junmin Quan
Format: Artigo
Language:Inglês
Published: MDPI AG 2026-04-01
Series:Vaccines
Subjects:
STING
cGAMP delivery
peptide coacervates
neoantigen
antitumor
Online Access:https://www.mdpi.com/2076-393X/14/4/329
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