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Multiplexed imaging reveals an IFN-γ-driven inflammatory state in nivolumab-associated gastritis

Summary: Immune checkpoint blockade using PD-1 inhibition is an effective approach for treating a wide variety of cancer subtypes. While lower gastrointestinal (GI) side effects are more common, upper gastrointestinal adverse events are rarely reported. Here, we present a case of nivolumab-associate...

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Hlavní autoři: Selena Ferrian, Candace C. Liu, Erin F. McCaffrey, Rashmi Kumar, Theodore S. Nowicki, David W. Dawson, Alex Baranski, John A. Glaspy, Antoni Ribas, Sean C. Bendall, Michael Angelo
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021-10-01
Edice:Cell Reports Medicine
Témata:
programmed death 1
nivolumab
gastritis
MIBI-TOF
interferon gamma
IFN-γ
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2666379121002810
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