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Multiplexed imaging reveals an IFN-γ-driven inflammatory state in nivolumab-associated gastritis

Summary: Immune checkpoint blockade using PD-1 inhibition is an effective approach for treating a wide variety of cancer subtypes. While lower gastrointestinal (GI) side effects are more common, upper gastrointestinal adverse events are rarely reported. Here, we present a case of nivolumab-associate...

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Principais autores: Selena Ferrian, Candace C. Liu, Erin F. McCaffrey, Rashmi Kumar, Theodore S. Nowicki, David W. Dawson, Alex Baranski, John A. Glaspy, Antoni Ribas, Sean C. Bendall, Michael Angelo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-10-01
Serier:Cell Reports Medicine
Fag:
programmed death 1
nivolumab
gastritis
MIBI-TOF
interferon gamma
IFN-γ
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666379121002810
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