Comparison of Whole Genome (wg-) and Core Genome (cg-) MLST (BioNumericsTM) Versus SNP Variant Calling for Epidemiological Investigation of Pseudomonas aeruginosa

Whole genome sequencing (WGS) is increasingly used for epidemiological investigations of pathogens. While SNP variant calling is currently considered as the most suitable method, the choice of a representative reference genome and the isolate dependency of results limit standardization and affect re...

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Autori principali:	Dominique S. Blanc, Bárbara Magalhães, Isabelle Koenig, Laurence Senn, Bruno Grandbastien
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2020-07-01
Serie:	Frontiers in Microbiology
Soggetti:	whole genome sequencing Pseudomonas aeruginosa molecular typing wgMLST cgMLST evaluation
Accesso online:	https://www.frontiersin.org/article/10.3389/fmicb.2020.01729/full
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