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Whole-genome sequencing-based typing methods for Clostridium butyricum strains from clinical, animal, plant, and environmental sources

ABSTRACT Clostridium butyricum exhibits a dual role, acting not only as a probiotic but also as an opportunistic pathogen associated with neonatal necrotizing enterocolitis (NEC) and infant botulism. We aimed to establish high-resolution genotyping frameworks to improve molecular surveillance and ou...

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Main Authors: Nadim Cassir, Victoria Mesa, Laurent Ferraris, Johanne Delannoy, Yousra Mikrat, Anthony Adjamian, Laure Diancourt, Christelle Mazuet, Frédéric Barbut, Bernard La Scola, Julio Aires
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2026-02-01
Series:Microbiology Spectrum
Subjects:
Clostridium butyricum
necrotizing enterocolitis
genotyping
wgMLST
cgMLST
cgSNP
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02619-25
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