Identification of NF-κB pathway-related biomarkers in myocardial ischemia-reperfusion injury: based on transcriptomics analysis and RT-qPCR validation

Abstract Myocardial ischemia-reperfusion injury (MIRI) limits the success of reperfusion therapies. Identifying potential biomarkers within the nuclear factor kappa-B (NF-κB) pathway is critical for developing new treatments. Transcriptomic data from mouse MIRI models were combined with NF-κB pathwa...

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Hlavní autoři:	Wang Ting, Xiao Helong, Wang Xiaoyu, Wang Chuanqiang, Hu Xiao, Yang Yang, Yuan Zhe, Xu Shaopeng, Geng Xiaoyong
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-04-01
Edice:	Scientific Reports
Témata:	Myocardial ischemia-reperfusion injury Nuclear factor kappa-B signaling pathway Transcriptomics Biomarkers Reverse transcription quantitative polymerase chain reaction (RT-qPCR)
On-line přístup:	https://doi.org/10.1038/s41598-026-47878-9
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