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Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole

Background/Aims: Lubeluzole is a benzothiazole derivative that has shown neuroprotective properties in preclinical models of ischemic stroke. However, clinical research on lubeluzole is now at a standstill, since lubeluzole seems to be associated with the acquired long QT syndrome and ventricular ar...

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Autori principali: Roberta Gualdani, Maria Maddalena Cavalluzzi, Francesco Tadini-Buoninsegni, Marino Convertino, Philippe Gailly, Anna Stary-Weinzinger, Giovanni Lentini
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Physiol Biochem Press GmbH & Co KG 2018-03-01
Serie:Cellular Physiology and Biochemistry
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Accesso online:https://www.karger.com/Article/FullText/488169
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