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Leveraging Machine and Deep Learning Algorithms for hERG Blocker Prediction

The human ether-a-go-go-related (hERG) gene is crucial in enabling the regulation of repolarisation process in the heart. Some chemicals act as hERG blockers, resulting in prolonged QT intervals. Predicting the binding capability of molecules with hERG channels is expected to reduce the burden of ca...

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書誌詳細
主要な著者: Syed Mohammad, Vaisali Chandrasekar, Omar Aboumarzouk, Ajay Vikram Singh, Sarada Prasad Dakua
フォーマット: Artigo
言語:Inglês
出版事項: IEEE 2025-01-01
シリーズ:IEEE Access
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オンライン・アクセス:https://ieeexplore.ieee.org/document/10982226/
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