PTIR1 acts as an isoform of DDX58 and promotes tumor immune resistance through activation of UCHL5
Summary: Cancer evades host immune surveillance by virtue of poor immunogenicity. Here, we report an immune suppressor, designated as PTIR1, that acts as a promotor of tumor immune resistance. PTIR1 is selectively induced in human cancers via alternative splicing of DDX58 (RIG-I), and its induction...
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| Principais autores: | , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2023-11-01
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| Serija: | Cell Reports |
| Teme: | |
| Online dostop: | http://www.sciencedirect.com/science/article/pii/S2211124723014006 |
| Oznake: |
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