ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.

Epithelial-mesenchymal transition (EMT) is a normal cell differentiation event during development and contributes pathologically to carcinoma and fibrosis progression. EMT often associates with increased transforming growth factor-β (TGF-β) signaling, and TGF-β drives EMT, in part through Smad-media...

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Principais autores:	Baby Periyanayaki Muthusamy, Erine H Budi, Yoko Katsuno, Matthew K Lee, Susan M Smith, Amer M Mirza, Rosemary J Akhurst, Rik Derynck
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2015-12-01
Serija:	PLoS Biology
Online dostop:	http://europepmc.org/articles/PMC4682977?pdf=render
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