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Recent studies of atomic‐resolution structures of tau protein and structure‐based inhibitors

Background Alzheimer’s disease (AD) is one of the most popular tauopathies. Neurofibrillary tangles and senile plaques are widely recognized as the pathological hallmarks of AD, which are mainly composed of tau and β‐amyloid (Aβ) respectively. Recent failures of drugs targeting Aβ have led scientist...

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Bibliografiske detaljer
Principais autores: Lili Zhu, Zhenyu Qian
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2022-03-01
Serier:Quantitative Biology
Fag:
Online adgang:https://doi.org/10.15302/J-QB-021-0271
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