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The effect of the use of omeprazole versus famotidine on the kidney transplant function: a randomized controlled study

Abstract Tacrolimus is metabolized in the liver with the participation of cytochrome P450 isoforms 3A4 and 3A5 (CYP3A4, CYP3A5). Omeprazole, unlike famotidine, is a substrate and inhibitor of CYP2C19, CYP3A4, CYP3A5 enzymes. The aim of the study is to compare the effect of omeprazole and famotidine...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Miłosz Miedziaszczyk, Marek Karczewski, Ilona Idasiak-Piechocka
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2025-01-01
Rangatū:Scientific Reports
Ngā marau:
Urunga tuihono:https://doi.org/10.1038/s41598-025-85534-w
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