The effect of the use of omeprazole versus famotidine on the kidney transplant function: a randomized controlled study
Abstract Tacrolimus is metabolized in the liver with the participation of cytochrome P450 isoforms 3A4 and 3A5 (CYP3A4, CYP3A5). Omeprazole, unlike famotidine, is a substrate and inhibitor of CYP2C19, CYP3A4, CYP3A5 enzymes. The aim of the study is to compare the effect of omeprazole and famotidine...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Nature Portfolio
2025-01-01
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| Serie: | Scientific Reports |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1038/s41598-025-85534-w |
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