Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.

Genetic alterations enhancing cell survival and suppressing apoptosis are hallmarks of cancer that significantly reduce the efficacy of chemotherapy or radiotherapy. The Inhibitor of Apoptosis Protein (IAP) family hosts conserved proteins in the apoptotic pathway whose over-expression, frequently fo...

Whakaahuatanga katoa

I tiakina i:

Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua:	Federica Cossu, Mario Milani, Patrice Vachette, Francesca Malvezzi, Serena Grassi, Daniele Lecis, Domenico Delia, Carmelo Drago, Pierfausto Seneci, Martino Bolognesi, Eloise Mastrangelo
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Public Library of Science (PLoS) 2012-01-01
Rangatū:	PLoS ONE
Urunga tuihono:	http://europepmc.org/articles/PMC3499469?pdf=render
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!

Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.

Ngā tūemi rite