SPG11 models reveal lysosomal calcium regulation of neural progenitor proliferation
Lysosome dysfunction has been widely implicated in many models of neurodegeneration, but much less is understood of its involvement during brain development in health and disease. Hereditary spastic paraplegia caused by mutations in the SPG11 gene is a neurodegenerative disorder characterized by lys...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2026-07-01
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| Series: | Neurobiology of Disease |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S0969996126001683 |
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