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Short incubation periods of atypical H-type BSE in cattle with EK211 and KK211 prion protein genotypes after intracranial inoculation

In 2006, a case of atypical H-type BSE (H-BSE) was found to be associated with a germline mutation in the PRNP gene that resulted in a lysine substitution for glutamic acid at codon 211 (E211K). The E211K amino acid substitution in cattle is analogous to E200K in humans, which is associated with the...

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Váldodahkkit: Eric D. Cassmann, Alexis J. Frese, Kelsey A. Becker, Justin J. Greenlee
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2023-11-01
Ráidu:Frontiers in Veterinary Science
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fvets.2023.1301998/full
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