Tau modulation through AAV9 therapy augments Akt/Erk survival signalling in glaucoma mitigating the retinal degenerative phenotype
Abstract The microtubule-associated protein Tau is a key player in various neurodegenerative conditions, including Alzheimer's disease (AD) and Tauopathies, where its hyperphosphorylation disrupts neuronal microtubular lattice stability. Glaucoma, a neurodegenerative disorder affecting the retina, l...
Збережено в:
| Автори: | , , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2024-06-01
|
| Серія: | Acta Neuropathologica Communications |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s40478-024-01804-0 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|