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Tonic GABAA receptor currents in Cerebellar Purkinje cells of wild-type and DMDmdx mice

Abstract Cerebellar Purkinje cells (PCs) fire spontaneously and depend heavily on inhibition to modify their activity. While phasic inhibition is well-described in PCs, the presence and mechanisms of tonic inhibitory currents, low amplitude currents resulting from ambient GABA acting upon extrasynap...

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Autors principals: Shaarang Mitra, Shailesh N. Khatri, Jason R. Pugh
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-12-01
Col·lecció:Scientific Reports
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Accés en línia:https://doi.org/10.1038/s41598-025-31919-w
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