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Use of Optogenetic Amyloid-β to Monitor Protein Aggregation in Drosophila melanogaster, Danio rerio and Caenorhabditis elegans

Alzheimer’s Disease (AD) has long been associated with accumulation of extracellular amyloid plaques (Aβ) originating from the Amyloid Precursor Protein. Plaques have, however, been discovered in healthy individuals and not all AD brains show plaques, suggesting that extracellular Aβ aggregates may...

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Bibliografiske detaljer
Principais autores: Prameet Kaur, Caroline Kibat, Emelyne Teo, Jan Gruber, Ajay Mathuru, Nicholas S Tolwinski
Format: Artigo
Sprog:Inglês
Udgivet: Bio-protocol LLC 2020-12-01
Serier:Bio-Protocol
Online adgang:https://bio-protocol.org/en/bpdetail?id=3856&type=0
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