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High-resolution optogenetics generates distinguishable neocortical activity patterns in awake mice

The neural basis of cognition is rooted in precisely coordinated population activity unfolding on the millisecond timescale. To causally probe these spatiotemporally intricate network dynamics, we developed a digital micromirror device (DMD)-based photostimulation platform featuring grid patterns wi...

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Principais autores: Ryosuke Yoshida, Yamato Ishii, Kotaro Yamashiro, Kei Furuya, Tianben Ding, Keisuke Goda, Nobuyoshi Matsumoto, Yuji Ikegaya
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-02-01
Serier:Neuroscience Research
Fag:
Optogenetics
Electrophysiology
Digital micromirror device
Patterned stimulation
Deep learning
Online adgang:http://www.sciencedirect.com/science/article/pii/S0168010225001956
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