A pan-cancer single cell landscape reveals heterogeneity and functional diversity of double-negative T cells

Abstract Background Double-Negative T (DNT) cells, lacking both CD4 and CD8 expression, play critical roles in cancer immunology, and have garnered increasing attention in cancer research. However, their heterogeneity and functional diversity within the tumor microenvironment (TME) remain underexplo...

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Xehetasun bibliografikoak

Egile Nagusiak:	Qing Hao, Tao Zhou, Huayun Yan, Zhixiang Ren, Wei Mao, Li-Bin Huang, Yue-yun Chen, Yuelan Wang, Minqin Xiao, Yajiao He, Xuyang Xia, Jing Wu, Wei-Han Zhang, Hai-Ning Chen, Maoxiang Qian, Feng Zhang, Li Yang, Lunzhi Dai, Huiyuan Zhang, Canhua Huang, Yang Shu, Yu Xu, Yang Luo, Yong Peng, Heng Xu
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2026-01-01
Saila:	Molecular Cancer
Gaiak:	Single-cell RNA sequencing Pan-cancer Double-Negative T cell Γδ T cell Tumor microenvironment Immunotherapy
Sarrera elektronikoa:	https://doi.org/10.1186/s12943-025-02548-8
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