Maintenance of graft tissue–resident Foxp3+ cells is necessary for lung transplant tolerance in mice

Mechanisms that mediate allograft tolerance differ between organs. We have previously shown that Foxp3+ T cell–enriched bronchus-associated lymphoid tissue (BALT) is induced in tolerant murine lung allografts and that these Foxp3+ cells suppress alloimmune responses locally and systemically. Here, w...

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Главные авторы:	Wenjun Li, Yuriko Terada, Yun Zhu Bai, Yuhei Yokoyama, Hailey M. Shepherd, Junedh M. Amrute, Amit I. Bery, Zhiyi Liu, Jason M. Gauthier, Marina Terekhova, Ankit Bharat, Jon H. Ritter, Varun Puri, Ramsey R. Hachem, Hēth R. Turnquist, Peter T. Sage, Alessandro Alessandrini, Maxim N. Artyomov, Kory J. Lavine, Ruben G. Nava, Alexander S. Krupnick, Andrew E. Gelman, Daniel Kreisel
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Clinical Investigation 2025-05-01
Серии:	The Journal of Clinical Investigation
Предметы:	Immunology Transplantation
Online-ссылка:	https://doi.org/10.1172/JCI178975
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