Multilocus inherited neoplasia allele syndrome (MINAS) in a Turkish cohort: molecular insights and clinical relevance for precision oncology

BackgroundMultilocus Inherited Neoplasia Allele Syndrome (MINAS) describes individuals who harbor pathogenic or likely pathogenic (LP/P) germline variants in two or more distinct cancer predisposition genes. With the broader implementation of next-generation sequencing (NGS) and multigene panel test...

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Κύριοι συγγραφείς:	Taha Bahsi, Serhat Seyhan, Kaan Helvaci, Umut Demirci, Irem Bilgetekin, Selami Bayram, Mehmet Akif Ozturk, Fatih Aydogan, Serkan Keskin, Kezban Pilanci, Nur Sener, Murat Tatlı, Hakan Harputluoglu, Esat Namal, Aysegul Kargi, Mukremin Uysal, Mahmut Ilhan, Cihan Erol, Naziyet Kose, Kerem Okutur, Halit Karaca, Erkan Dogan, Veli Berk, Ahmet Siyar Ekinci, Mustafa Ozdogan
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2025-12-01
Σειρά:	Frontiers in Pharmacology
Θέματα:	MINAS germline variants multigene panel BRCA Turkish cohort hereditary cancer
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1672774/full
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