Mitochondrial transplant activates Ca2+/TFAP2A to promote hDPSCs-mediated dentin-pulp regeneration

Abstract Background The dentin-pulp complex (DPC) is composed of the odontoblastic layer and associated stromal components. It serves key functions in immunological homeostasis and tissue regeneration of dental tissues. Human dental pulp stem cells (hDPSCs) have emerged as pivotal cells for DPC rege...

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Detalhes bibliográficos

Principais autores:	Peimeng Zhan, Xinfang Zhang, Zhuo Xie, Lingling Chen, Shuheng Huang, Qiting Huang, Zhengmei Lin, Runfu Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-03-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Mitochondrial transplantation Human dental pulp stem cells Odontoblast differentiation Dentin-pulp complex regeneration Tissue engineering
Acesso em linha:	https://doi.org/10.1186/s13287-026-04949-y
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