क्यूआर कोड

CYD0281, a Bcl-2 BH4 domain antagonist, inhibits tumor angiogenesis and breast cancer tumor growth

Abstract Background B-cell lymphoma 2 (Bcl-2) family proteins are key regulators of apoptosis, which possess four conserved Bcl-2 homologies (BH) domains. Among the BH domains, the BH3 domain is considered as a potent ‘death domain’ while the BH4 domain is required for anti-apoptotic activity. Bcl-2...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Yihua Lin, Yiling Zhao, Minggui Chen, Zishuo Li, Qiao Liu, Jian Chen, Yi Ding, Chunyong Ding, Ye Ding, Cuiling Qi, Lingyun Zheng, Jiangchao Li, Rongxin Zhang, Jia Zhou, Lijing Wang, Qian-Qian Zhang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BMC 2023-05-01
श्रृंखला:BMC Cancer
विषय:
CYD0281
B-cell lymphoma 2 (Bcl-2)
Bcl-2 homology (BH) domains
BH4 domain antagonist
Apoptosis
Angiogenesis
ऑनलाइन पहुंच:https://doi.org/10.1186/s12885-023-10974-4
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